Their opponents are chasing a Champions League place but have not won in the league in their last four games.
What time is kick-off?
THIS game takes place on Wednesday, January 24.
The match will be held at the Stadio Luigi Ferraris.
Kick-off time is at 7.45pm.
What is the team news?
ROMA manager Eusebio Di Francesco has no new injury or suspension concerns for the midweek clash.
The hosts will be on a high after drawing with Inter Milan at the weekend which saw them move to just three points off the Champions League spots.
Marco Giampaolo is expected to name a similar squad to the one which beat Fiorentina 3-1 over the weekend.
Jacopo Sala remains suspended after getting a straight red card in the 3-2 defeat to Benevento.
My bet for tonight:
Sampdoria v Roma – DRAW with odds 3,60
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